Developmental disruptions underlying brain abnormalities in ciliopathies
نویسندگان
چکیده
منابع مشابه
Developmental disruptions underlying brain abnormalities in ciliopathies
Primary cilia are essential conveyors of signals underlying major cell functions. Cerebral cortical progenitors and neurons have a primary cilium. The significance of cilia function for brain development and function is evident in the plethora of developmental brain disorders associated with human ciliopathies. Nevertheless, the role of primary cilia function in corticogenesis remains largely u...
متن کاملBrain metabolic abnormalities associated with developmental venous anomalies.
BACKGROUND AND PURPOSE Developmental venous anomalies are the most common intracranial vascular malformation and are typically regarded as inconsequential, especially when small. While there are data regarding the prevalence of MR imaging findings associated with developmental venous anomalies, FDG-PET findings have not been well-characterized. MATERIALS AND METHODS Clinical information syste...
متن کاملThe developmental disruptions of serotonin signaling may involved in autism during early brain development.
Autism is a developmental disorder defined by the presence of a triad of communication, social and stereo typical behavioral characteristics with onset before 3years of age. In spite of the fact that there are potential environmental factors for autistic behavior, the dysfunction of serotonin during early development of the brain could be playing a role in this prevalence rise. Serotonin can mo...
متن کاملDevelopmental disruptions in neural connectivity in the pathophysiology of schizophrenia.
Schizophrenia has been thought of as a disorder of reduced functional and structural connectivity. Recent advances in neuroimaging techniques such as functional magnetic resonance imaging, structural magnetic resonance imaging, diffusion tensor imaging, and small animal imaging have advanced our ability to investigate this hypothesis. Moreover, the power of longitudinal designs possible with th...
متن کاملEquine Dental Developmental Abnormalities
Abnormalities of dental development and eruption occur quite commonly in the horse and result in a wide range of clinical conditions. A congenital/developmental problem present at the time of tooth eruption often leads to acquired dental problems as the teeth continue to erupt and wear. Consequently, several different dental abnormalities whose pathogenesis may be inter-related, are often prese...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2015
ISSN: 2041-1723
DOI: 10.1038/ncomms8857